Phytochemical standard, Nobiletin, analytical standard, Supelco®

Leverandør: Merck
92600-10MGEA 5300 NOK
92600-10MG
Phytochemical standard, Nobiletin, analytical standard, Supelco®
Standarder Organiske standarder
Nobiletin suppresses the expression of matrix metalloproteinases 1, 3 and 9, which participate in the break down of the extracellular matrix during tumor metastasis. Nobiletin is also involved in the increased expression of tissue inhibitor of matrix metalloproteinase 1 further preventing extracellular matrix degradation during tumor invasion. This bioflavonoid is believed to achieve both of these functions by disrupting the signal transduction pathway of Ras-Raf-MEK.
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